Researchers find a new way to kill cancer cells

Researchers find a new way to kill cancer cells
One way to kill the tumour could be starving them of their life-sustaining fuel.

To test their hypothesis that these particular cancers needed fats to survive and that PHD3 was a key regulator in the fat-burning process fuelling tumour growth, the researchers restored to normal the levels of PHD3 in a line of cancer cells and in mice.  The tumours not only stopped growing, they died. ‘That was really exciting,’ Haigis said. ‘We’ve altered a lot of metabolic pathways in cancer, and this is one of the few pathways we’ve modulated where we really see the tumours die. They are so dependent on fat oxidation that they die,’ Haigis noted. Before this discovery can move ahead to the clinic, she said, more basic research needs to be done, both in animal models and in cancer cells taken from patients, to understand why certain tumours depend on fat. Here is everything you need to know about latest advances in cancer treatment.

Source: IANS

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